现代变量选择方法在青少年近视研究中的应用

doi:10.7523/j.issn.2095-6134.2015.06.002

中国科学院大学学报 ›› 2015, Vol. 32 ›› Issue (6): 728-734.DOI: 10.7523/j.issn.2095-6134.2015.06.002

现代变量选择方法在青少年近视研究中的应用

海豹¹, 李仕明², 刘洛如³, 申立勇¹, 张三国¹, 李偲圆², 李翯³, 康梦田², 孙芸芸², 孟博², 张庆昭¹

1. 中国科学院大学数学科学学院, 北京 101408;
2. 首都医科大学附属北京同仁医院眼科中心, 北京 100730;
3. 河南安阳市眼科医院, 河南安阳 455000

收稿日期:2014-09-25 修回日期:2015-03-16 发布日期:2015-11-15
通讯作者: 张三国
基金资助:
国家973重点基础研究发展计划项目(2011CB504601)资助

Juvenile myopia study using modern variable selection methods

HAI Bao¹, LI Shiming², LIU Luoru³, SHEN Liyong¹, ZHANG Sanguo¹, LI Siyuan², LI He³, KANG Mengtian², SUN Yunyun², MENG Bo², ZHANG Qingzhao¹

1. School of Mathematical Sciences, University of Chinese Academy of Sciences, Beijing 101408, China;
2. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;
3. Anyang Eye Hospital, Anyang 455000, Henan, China

Received:2014-09-25 Revised:2015-03-16 Published:2015-11-15

摘要/Abstract

摘要：

通过分析一组医学数据挖掘出影响青少年近视的关键因素,建立青少年近视患病概率预测模型.数据集主要由两部分组成:一是青少年眼睛的医学测量数据,二是由生活学习习惯调查问卷得到的数据.采用几种现代统计学方法,并利用ROC曲线得到较优的患病概率模型.结果表明,性别、眼轴长度、角膜曲率、工作日睡眠时间、不戴眼镜远视力、远距离调节反应等因素对青少年近视有重要的影响作用,并由此建立预测模型.

关键词: 变量选择, logistic回归, Lasso, MCP, ROC曲线

Abstract:

In this work we used some variable-selection techniques to find out the relevant factors that cause adolescent myopia, and established probabilistic models for myopia prediction. The research is based on a medical dataset consisting of two parts: medical measurement data of the youths and data on daily living habits obtained by questionnaire survey. We used some modern variable selection methods and the ROC curve to evaluate different modes. The results show that gender, axial length, corneal curvature, weekday sleeping time, distance vision without glasses, and remote adjustment reaction have important influences on adolescent myopia.

Key words: variable selection, classical logistic regression, Lasso, MCP, ROC curve

中图分类号:

海豹, 李仕明, 刘洛如, 申立勇, 张三国, 李偲圆, 李翯, 康梦田, 孙芸芸, 孟博, 张庆昭. 现代变量选择方法在青少年近视研究中的应用[J]. 中国科学院大学学报, 2015, 32(6): 728-734.

HAI Bao, LI Shiming, LIU Luoru, SHEN Liyong, ZHANG Sanguo, LI Siyuan, LI He, KANG Mengtian, SUN Yunyun, MENG Bo, ZHANG Qingzhao. Juvenile myopia study using modern variable selection methods[J]. , 2015, 32(6): 728-734.

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现代变量选择方法在青少年近视研究中的应用

Juvenile myopia study using modern variable selection methods

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