收稿日期: 2001-04-24
网络出版日期: 2001-01-10
基金资助
中国科学院知识创新工程重要学科方向项目 (kscx 2 3 0 2 0 1)
Glycobiology-Essential for Discovery of Gene's Function
Received date: 2001-04-24
Online published: 2001-01-10
金城 . 糖生物学——破解基因组功能的必由之路[J]. 中国科学院大学学报, 2001 , 18(1) : 66 -75 . DOI: 10.7523/j.issn.2095-6134.2001.1.011
This paper overviews the significance, advances and future direction in the glycobiology field. Special emphasis is given to cell cell adhesion which is mediated by the interaction between carbohydrates and carbohydrates binding proteins (CBP). The roles of carbohydrates in the folding of nascent polypeptides, immune system, and cellular signal transductions are also reviewed. The scope also covers carbohydrates in infections, carbohydrates in diseases,and chemical synthesis/structural analysis of carbohydrates. Finally,the features and future directions of glycobiological research are pointed out by the author.
Key words： carbohydrate; glycobiology; glycomics; glycoconjugate
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