呼伦贝尔草原不同环境介质中特定抗生素耐药性基因的分布与演变特征（英文）
Distribution and evolution of certain antibiotic resistance genes in different environmental media in Hulunbuir Grassland
Received date: 2024-11-13
Revised date: 2025-03-04
Online published: 2025-04-09
Supported by
the National Natural Science Foundation of China(41775135);the National Natural Science Foundation of China(42275138)
李圆圆 , 郭立 , 杜睿 , 赵华 , 贾泽宇 . 呼伦贝尔草原不同环境介质中特定抗生素耐药性基因的分布与演变特征（英文）[J]. 中国科学院大学学报, 2026 , 43(3) : 336 -349 . DOI: 10.7523/j.ucas.2025.007
We measured the relative abundance of antibiotic resistance genes （ARGs） related to the treatment of brucellosis by quantitative real-time polymerase chain reaction （PCR）， characterized the bacterial composition by 16S rRNA gene sequencing， and analysed the relationships between ARGs and bacteria by network analyses in multiple environmental media samples （rainwater， topsoil and PM2.5） collected in the summers from 2019 to 2021. The three environmental media of Hulunbuir Grassland were contaminated with some degree of ARGs with the highest ARG abundance in the topsoil. Significant relationships were observed between ARGs and bacteria， thereby promoting the spread of antibiotic resistance. Extensive distribution of ARG carrying bacteria in atmospheric particles， rainwater， and soil may also increase potential ARG exposure risks. These findings are valuable in understanding the ARG pollution levels and distribution characteristics in three environmental media， which can aid to design and implement policies to curb ARGs in local areas.
Key words： ARGs; distribution; abundance; evolution; multiple environmental media; Hulunbuir Grassland
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