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中国科学院大学学报 ›› 2016, Vol. 33 ›› Issue (3): 354-359.DOI: 10.7523/j.issn.2095-6134.2016.03.011

• 化学与生物学 • 上一篇    下一篇

α-淀粉酶活性对不对称重力大小与方向的依赖性

袁龙飞1,2, 刘荣4, 周影2, 肖亚婷2, 何裕建2,3   

  1. 1. 中国科学院动物研究所农业虫害鼠害综合治理研究国家重点实验室, 北京 100101;
    2. 中国科学院大学化学与化工学院, 北京 100049;
    3. 北京大学天然药物及仿生药物国家重点实验室, 北京 100191;
    4. 中国科学院植物研究所系统与进化植物学国家重点实验室, 北京 100093
  • 发布日期:2016-05-15
  • 通讯作者: 何裕建
  • 基金资助:

    Supported by National Natural Science Foundation of China (21272263,31501667), State Key Laboratory of Natural and Biomimetic Drugs (K20140204), and University of Chinese Academy of Sciences (O8JT011J01)

Dependence of α-amylase activity on magnitude and direction of asymmetric gravity field

YUAN Longfei1,2, LIU Rong4, ZHOU Ying2, XIAO Yating2, HE Yujian2,3   

  1. 1. State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;
    2. School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, China;
    3. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China;
    4. State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
  • Published:2016-05-15
  • Supported by:

    Supported by National Natural Science Foundation of China (21272263,31501667), State Key Laboratory of Natural and Biomimetic Drugs (K20140204), and University of Chinese Academy of Sciences (O8JT011J01)

摘要:

手性有左右之分.对于重力,可人为产生左、右手螺旋力.通过光谱学手段,考察不对称重力大小及方向变化对α-淀粉酶活性的影响.结果表明,在1~9 000 g范围内,超重力的增加能够逐渐提高α-淀粉酶活性,并且右手螺旋力比左手螺旋力对于α-淀粉酶活性具有更强的激活作用.考虑到地球天然重力昼夜周期性变化的事实和酶活性对重力大小与方向的依赖性,重力24 h的周期变化可能是昼夜生理节律产生的重要力学原因之一.

关键词: 不对称重力场, α-淀粉酶, 酶活性, 生物节律

Abstract:

Asymmetry is often designated as right- and left-handed. The right- and left-handed helical hypergravity (HG) field can be artificially produced. In this paper, it is shown that the α-amylase activity is dependent on both the magnitude and direction of HG within the range between 1 g and 9 000 g. The right-handed HG has larger enhanced effect on enzyme activity than the left-handed HG. Considering the circadian rhythm of natural gravity on the earth, it is suggested that circadian rhythm of natural gravity may be an important mechanical factor for the origin of biological circadian rhythms.

Key words: asymmetric gravity field, α-amylase, enzyme activity, biological circadian rhythms

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