苄基异喳啉生物碱在木兰亚纲等植物类群中的分布

中国科学院大学学报

苄基异喳啉生物碱在木兰亚纲等植物类群中的分布

朱敏, 肖培根

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1991-03-10 发布日期:1991-03-10
通讯作者: 朱敏

Distribution of Benzylisoquinolines in Magnoliidae and Other Taxa

Zhu Min, Xiao Pei-Gen

Received:1900-01-01 Revised:1900-01-01 Online:1991-03-10 Published:1991-03-10
Contact: Zhu Min

摘要/Abstract

摘要：

本文详细讨论了苄基异喹啉生物碱的生源和进化趋势，化学结构类型的分布规律，植

物来源，药理作用以及它们之间的联系性。研究表明：苄基异喹啉生物碱主要存在于较原始

的木兰亚纲植物群中，阿朴菲型、双苄基异喹啉型、原小檗碱型为普遍存在的结构类型。由于

按生源路线产生的不同结构类型在植物中呈现有规律的分布，因此苄基异喹啉生物碱可作为

很好的分类学指标。

关键词: 苄基异喹啉生物碱, 木兰亚纲, 化学分类

Abstract:

Based on the analysis of benzylisoquinoline alkaloids of 323 samples in 11 fami-

lies, 50 genera and 181 species of the Chinese flora discussed in this paper are the biogenesis,

evolution, distribution pattern and botanical sources as well as the pharmacological action of

this specific category of alkaloids.

Benzylisoquinoline alkaloids are found mainly in Magnoliidae, in which aporphines,

bisbenzylisoquinolines and protoberberines are the three major types of the alkaloids. More

specifically, aporphines appeare more concentrated in primitive woody plants such as the

Annonaceae, while bisbenzylisoquinolines are especially common in the Menispermaceae,

Thalictrum (the Ranunculaceae) and Berberis (the Berberidaceae). As to protoberberines, the

quaternary ones occur mainly in the families Ranunculaceae and Berberidaceae, whereas the

tertiary ones mainly in the relatively advanced families Menispermaceae and Papaveraceae

within Magnoliidae.

As a whole, a general rule can be drawn that the simpler the chemical structure of the

benzylisoquinolines is, the more widely they are distributed in primitive groups; more specific

ones only have a limited distribution in more advanced groups or even within one family or

one to several genera. This general pattern of distribution of benzylisoquinoline alkaloids in

plants may be of value as a taxonomic criterion for plant systematics.

Furthermore, this group of alkaloids covers the gamut of pharmacologic responses, such

as the antibacterial effect and the effect to cardiovascular and nervous systems, and

consequently the correlation between benzylisoquinoline alkaloids and their pharmacologic

activities within Magnoliidae may worthily be applied for the finding of new drugs.

Key words: Benzylisoquinoline alkaloids, Magnoliidae, Chemotaxonomy

朱敏, 肖培根. 苄基异喳啉生物碱在木兰亚纲等植物类群中的分布[J]. 中国科学院大学学报.

Zhu Min, Xiao Pei-Gen. Distribution of Benzylisoquinolines in Magnoliidae and Other Taxa[J]. .

[1]	宋湛谦,梁志勤,刘星. 白皮松松脂的化学特征及其分类学意义[J]. 中国科学院大学学报, 1998, 36(6): 511-514.
[2]	胡梅, 肖培根. 杜鹃属植物的化学分类学研究[J]. 中国科学院大学学报, 1992, 30(3): 226-238.
[3]	黄远征, 陈树群, 何宗英, 陈全友, 吴云伦. 巴柑檬及其近缘种的精油成分和化学分类研究[J]. 中国科学院大学学报, 1992, 30(3): 239-244.
[4]	朱敏, 肖培根. 中国唐松草属植物的化学系统学初探[J]. 中国科学院大学学报, 1991, 29(4): 358-369.
[5]	马忠武, 何关福, 印万芬, 潘炯光, 徐植灵. 白豆杉叶精油成分的研究与化学分类[J]. 中国科学院大学学报, 1991, 29(1): 67-70.
[6]	李德铢, 邱声祥, 吴征镒. 鹅绒藤类群的化学分类[J]. 中国科学院大学学报, 1990, 28(6): 461-466.
[7]	马忠武, 何关福, 印万芬. 三尖杉属(科)植物的双黄酮成分及其化学分类的研究[J]. 中国科学院大学学报, 1990, 28(2): 122-128.
[8]	陶光复, 钟扬. 湖北樟属数量化学分类研究[J]. 中国科学院大学学报, 1988, 26(6): 409-417.
[9]	毕培曦, 江润祥, 李钳, 张宏达, Chang Kiaw-Lan, Wong Khoon-Meng, Gray Alexander I., Waterman Peter G.. 芸香科九里香属及美栌木属的化学分类[J]. 中国科学院大学学报, 1988, 26(3): 205-210.
[10]	毕培曦, 江润祥, 吴锦洪, 张宏达, 李钳, 余世孝, Waterman Peter G.,. 国产芸香科九里香属化学分类[J]. 中国科学院大学学报, 1986, 24(3): 186-192.
[11]	郝小江, 杨崇仁, 陈泗英, 周俊. 国产乌头属的化学分类[J]. 中国科学院大学学报, 1985, 23(5): 321-335.