mproved Process of Synthesis of α-Hydroxycyclohexylphenylketone
Received date: 2000-11-02
Online published: 2002-03-18
胡应喜 , 刘霞 , 李燕芸 , 张明霞 , 刘利红 , 石彩云 . 光敏引发剂α-羟基环己基苯甲酮合成的改进[J]. 中国科学院大学学报, 2002 , 19(2) : 182 -185 . DOI: 10.7523/j.issn.2095-6134.2002.2.015
α-Hy dro xycyclohexy lphenylketone is sy nthesized after four steps of reactions w ith benzaldehyde,bromocy clohexane and bromi ne as main raw material.T he oxygenizement reactio n and bromination reactions of the process are improved.T he second step react ion can react wit h chlorofo rm as solvent and benzalkonium bromide solution as phase transfer catalyst in room temperature.In cont rast to previous technology, by-products are fewer, t reat ments are simpler, and y ield is higher.The t hird step reaction, bromination reac-tion can react wi th tetrachloromethane as solvent and acetic acid as catalyst.T he characterstics of the im-proved method are simple technology, low cost and hig h yields.
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