Journal of University of Chinese Academy of Sciences >
Building of Mathematic Models for High-Throughput Screening
Received date: 2003-05-14
Revised date: 2003-09-15
Online published: 2004-05-10
In high throughput screening process, mathematic models are regarded as the foundations for large scale screening for compound library and automating the process. With thermodynamics and kinetics as the means, the article provides synthetically dynamic models by analyzing the principle of screening. Meanwhile, the article also analyzes three probable interactions between drugs and targets, and deduces corresponding mathematic models.
LI SongJun , LIU BaiLing , HU Jie . Building of Mathematic Models for High-Throughput Screening[J]. Journal of University of Chinese Academy of Sciences, 2004 , 21(3) : 333 -339 . DOI: 10.7523/j.issn.2095-6134.2004.3.008
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