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DOI: https://doi.org/10.7523/j.ucas.2025.026

A Study on the Microbiome in the Obstetric Outpatient Environment of Hospital

  • YIN Naiyin ,
  • GAO Huimin ,
  • XIONG Shimao ,
  • WU Yue ,
  • JIANG Xiyan ,
  • XIAO Peng ,
  • ZHAO Fang ,
  • LI Rui ,
  • CAI Xiaolin ,
  • LIU Ruyin ,
  • CUI Yanshan
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  • 1 College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China;
    2 Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China

Received date: 2025-03-04

  Revised date: 2025-04-22

  Online published: 2025-07-17

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Abstract

The structure of microbial communities and the distribution of antibiotic resistance genes (ARGs) in hospital environments may have potential impacts on early life. This study collected 35 dust samples from the obstetrics outpatient environment of a tertiary hospital in Beijing and analyzed the microbial communities and ARGs using metagenomic sequencing technology. The analysis revealed 17 microbial phyla in the samples, among which Actinobacteria, Proteobacteria, and Firmicutes emerged as the dominant groups, with their cumulative relative abundance reaching 97.66%. Significant differences in microbial presence were observed among various locations, with higher diversity found in high-contact areas. In total, 182 types of ARGs and 91 types of antibiotics were identified, with the cumulative abundance of vancomycin and tetracycline classes reaching 44.95%. Through binning, a total of 111 types of bacteria corresponding to ARG hosts were identified, among which Cutibacterium acnes and Lactobacillus curvatus are the main contributors. This study provides important data for understanding the distribution of microbial communities and ARGs in the hospital maternity outpatient environment and may offer a scientific basis for infection prevention and control strategies in hospitals.

Key words： obstetrics outpatient; metagenomic sequencing; microbial communities; pathogens; antibiotic resistance genes

Cite this article

YIN Naiyin , GAO Huimin , XIONG Shimao , WU Yue , JIANG Xiyan , XIAO Peng , ZHAO Fang , LI Rui , CAI Xiaolin , LIU Ruyin , CUI Yanshan . A Study on the Microbiome in the Obstetric Outpatient Environment of Hospital[J]. Journal of University of Chinese Academy of Sciences, 0 : 2025020 -2025020 . DOI: 10.7523/j.ucas.2025.026

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