MIL-STD-1553B Bus is a standard bus which has been adopted in electronic networks of aviation, spaceflight, military etc. Our research project adopts SOPC（System On a Programmable Chip） with PowerPC405 processor hardcore embedded in FPGA to construct the remote terminal (RT) of 1553B bus with DDC’s 65170 protocol chip. In this paper, the basic points of PowerPC405 processor hardcore and Virtex-II Pro FPGA, the method of implementing HW/SW , the result of validation have been introduced.