关键词: 离心力场, 异佛尔酮, 不对称合成, 圆二色光谱, 螺旋运动, 对映体过量

Abstract: In this paper, asymmetric synthesis of oxidation reaction of achiral isophorone influenced by artificial centrifugal force field was studied. The reaction system was characterized by UV, Infrared (IR) and Circular dichroism (CD). The CD230 of product mixture was positive and negative in the clockwise and anticlockwise rotation,respectively, and the effect was dependent on the rotation speed. The data indicated that enantiomeric excess of isophorone oxide was able to be caused by the external centrifugal force field. It was suggested that the chiral effect was resulted from the chiral interaction between the chiral right- and left- handed helical motion and the chiral enantiomers.

Key words: centrifugal force field, isophorone , asymmetric synthesis, circular dichroism (CD), helical motion, enantiomeric excess