Development of 2,4,6-Triiodophenol Microspheres with Ethylcellulose

doi:10.7523/j.issn.2095-6134.2005.5.007

›› 2005, Vol. 22 ›› Issue (5): 575-578.DOI: 10.7523/j.issn.2095-6134.2005.5.007

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Development of 2,4,6-Triiodophenol Microspheres with Ethylcellulose

LIU Rui-Li¹, JIANG Qing-Jun², LIU Shi-Yuan², LI Wen-Xin¹

1. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China;
2. Second Military Medical University, Shanghai 200433, China

Received:2004-07-26 Revised:2004-10-14 Online:2005-09-15

Abstract

Abstract:

In this paper,2,4,6-triiodophenol-ethylcellulose microsphere was developed by in2liquid drying method, in order to increase the granularity of the X2ray CT contrast agent and to prevent the blood vessel X-ray CT contrast agent from exuding through the vascular wall to the tissue. The influences of the composition ratio of 2,4,6-triiodophenol : ethylcellulose to the microspheres ’ appearance and diameter, and the entrapment of 2,4,6-triiodophenol were studied. It was found that when the composition ratio was 1∶2, the microspheres’ appearance was round, the average diameter was only 3168μm, and the entrapment of 2,4,6-triiodophenol was 4114 %.

Key words: in-liquid drying method,2,4,6-triiodophenol, ethylcellulose microsphere, blood vessel X-ray CT contrast agent

CLC Number:

LIU Rui-Li, JIANG Qing-Jun, LIU Shi-Yuan, LI Wen-Xin. Development of 2,4,6-Triiodophenol Microspheres with Ethylcellulose[J]. , 2005, 22(5): 575-578.

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Development of 2,4,6-Triiodophenol Microspheres with Ethylcellulose

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